Percutaneous Transvenous Coil Embolization Treatment for Liver Shunts

Last year, we published a post on a promising new procedure, Percutaneous Transvenous Coil Embolization (PTCE) for the repair of liver shunts. The first scientific paper has come out on this procedure, and Dr. Cassie Lux, Assistant Professor of Surgery at the College of Veterinary Medicine at the University of Tennessee, very generously wrote up for us how the procedure works:

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Promising New Procedure for Liver (Portosystemic) Shunts

Update: This procedure is now available at several locations around the country, and we have published additional information on it here and here.

Some promising news regarding correcting portosystemic shunts in dogs comes from U.C. Davis, where Dr. Bill Culp has developed a new, non-invasive way to close intrahepatic shunts, which historically have been difficult to correct surgically.

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Dr. Guillermo Couto, who was spearheading the fibrinolysis research at Ohio State University, has retired, and no one there is continuing this research. Right now, we only suspect that some Deerhounds with bleeding issues have the same problem as Greyhounds, which is suspected to be fibrinolysis. To help us decide what the best next step would be, we thought we would collect some anecdotal information that will help us to determine whether aminocaproic acid helps Deerhounds with post-operative bleeding as it does Greyhounds.

If you have a dog that experiences post-surgical bleeding and the administration of aminocaproic acid stops the bleeding, we would be very interested to hear about that. If you administered aminocaproic acid during a bleeding episode and your dog did not stop bleeding, or your dog starts to bleed even though you were giving your dog aminocaproic acid prophylactically, we would be interested to hear about those experiences, too. As always, your information will be kept confidential. For more information on using aminocaproic acid for post-operative bleeding, go to http://sdcahealth.wordpress.com/health-issues/bleeding-problems/fibrinolysis/.

Please send this information to John Dillberger at P.O. Box 2118, Nashville, IN 47448-2118; (812) 988-6175; or at John “at” Greymorn.com. Please help us to determine whether aminocaproic acid works or not so we know the best next steps to take concerning this problem.

 

Announcement from the University of Pennsylvania for a clinical trial for hemangiosarcoma:

Further Evaluation of the Benefits of a Traditional Chinese Medicine Supplement for Dogs with Splenic Hemangiosarcoma

Dec 6, 2013
In a previous study conducted here at PennVet, the mushroom supplement I’m-Yunity® significantly increased survival time in dogs with splenic hemangiosarcoma. I’m-Yunity® extract effectively delivers the standardized ingredient polysaccharopeptide (PSP) which can only be isolated from the Coriolus Versicolor mushroom.

In this new trial, we will be comparing I’m-Yunity’s® effect on survival time and quality of life to the standard chemotherapy treatment.

Dogs will randomly be chosen to receive either chemotherapy, I’m-Yunity® treatment, or both concurrently, and owners will not know to which treatment group their dog was assigned. Dogs enrolled in this study will have 11 weekly visits, followed by monthly follow-up visits until the end of their life.

Eligibility:

  • Diagnosis of hemangiosarcoma following splenectomy.
  • At least 4 kg.
  • Not currently undergoing treatment for cancer.
  • No other significant health concerns that are an immediate threat to life.
  • Ability to administer oral medication (pills) to your dog.

Please contact the VCIC at 215-573-0302 or vcic@vet.upenn.edu for more information about this study.

Chinese Medicine Holdings, the makers of I’m-Yunity supplement, is the sponsor of both studies,  but both studies were designed by the Penn clinical epidemiologist, who is also the principle investigator.